GWS have regained Jesse Hogan and Tom Green for the huge AFL derby against Sydney, while Port Adelaide have recalled captain Tom Jonas for their crunch clash with Geelong.
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And ladder leaders Collingwood have left Mason Cox out of their starting side for the clash with Hawthorn after the American forward's lean few weeks.
Cox, who was filthy when substituted out of last week's defeat to Carlton, has been named on the emergency list for Saturday's MCG tussle.
Ash Johnson returns at Cox's expense, with Bobby Hill also back after illness sidelined him last week.
The Hawks have lost defender Sam Frost (foot) and will again be without wingman Karl Amon (knee).
The Western Bulldogs have regained Liam Jones from a broken arm and Ed Richards from illness to bolster their defence against Richmond in a huge Marvel Stadium contest on Friday night.
Josh Bruce, Alex Keath and Ryan Gardner are all out injured for the Dogs, while the Tigers have regained co-captain Toby Nankervis from suspension and Jayden Short from injury.
But Richmond have decided to rest gun veterans Trent Cotchin and Dustin Martin following a short five-day break as they seek to replace the Bulldogs in the top eight.
The Giants are on a club-record seven-match winning streak and can strengthen their grip on a finals spot with victory over neighbours Sydney on Saturday night.
The return of key forward Hogan (quad) and star midfielder Green (hamstring) is a huge boost against a Swans side that has lost Lance Franklin, Dane Rampe and Justin McInernery to injuries.
Star forward Franklin announced his retirement this week after succumbing to a calf injury, while Sydney have recalled ruckman Tom Hickey and defender Aaron Francis.
Port skipper Jonas has fallen out of favour at Alberton, managing just one senior appearance since round 10.
But the door has opened for his return against Geelong at GMHBA Stadium on Saturday night after fellow key defender Aliir Aliir was placed under concussion protocols.
Lachie Jones will also miss with concussion after his head clash with Aliir during last week's Showdown, while livewire forward Willie Rioli returns.
The Cats have lost Mark Blicavs and Tom Hawkins to injury but regain versatile tall Esava Ratugolea as they desperately seek to keep their premiership defence alive.
Adelaide have regained talented forward Josh Rachele from suspension for Saturday's clash with fellow finals hopefuls Gold Coast, who will be without co-captain Touk Miller.
Miller was handed a one-match ban on Thursday for making contact with the Brisbane Lions' Dayne Zorko's groin region.
Still in the top-eight hunt, Essendon have handed high-end draft pick Elijah Tsatas his debut against a West Coast side chasing back-to-back wins for the first time this season.
The Eagles have been bolstered by the return of experienced defender Jeremy McGovern.
Carlton have lost injury-riddled defender Mitch McGovern - Jeremy's brother - to another hamstring injury ahead of Sunday's clash with fellow top-eight side St Kilda.
The Blues are already missing gun midfielders Sam Walsh and Adam Cerra because of hamstring injuries.
Australian Associated Press
