Get Started has taken the 742-square metre space previously occupied by MediaCom, and will pay $500 a square metre gross in rent, discounted by a sub-20 per cent incentive.

The six-year leasing deal was strung by JLL agents Zak Seccull and Nick Drake, acting on behalf of the Drapac Group.

Mr Seccull said MediaCom had left behind a high-quality fit-out so the incentive was manifested as a discount in the rent.

"Given the state of the leasing market in Melbourne and the unusually long lease for a space of that size, there was some abatement in the rent," he said.

Smaller media and advertising agencies are attracted to the Georges building which is anchored by industry heavyweights George Patterson Y&R. But Get Started chief Marty Drill said businesses were looking for more than just an advertising agency.

"The very fact that a digital agency like us has moved into an advertising hub such as Georges is symbolic of that industry change," Mr Drill said.

The Drapac Group recently sold the leasehold on the Georges building for around $8 million to a local private investor. The lease which expires in 2019 has a further 20-year option.

Leasing agents are reporting an increase in leasing enquiries. Savills agent Mark Rasmussen said enquiry for space covering more than 1000 square metres is up around 60 per cent this year.

"There's enquiry for up to 70,000 square metres compared with under 50,000 square metres this time last year," Mr Rasmussen said.

Melbourne's vacancy rate of 9.2 per cent had peaked and would start to fall following the stalled Telstra tower and the expectation of an increase of staff at the major banks and the state government, he said.